2021 Challenger de Santiago III – Doubles

Diego Hidalgo and Nicolás Jarry were the defending champions but only Hidalgo chose to defend his title, partnering Sergio Galdós. Hidalgo lost in the quarterfinals to Hans Hach Verdugo and Miguel Ángel Reyes-Varela.

Evan King and Max Schnur won the title after defeating Hach Verdugo and Reyes-Varela 3–6, 7–6(7–3), [16–14] in the final.

Seeds
• # 🇧🇷 Rafael Matos / 🇧🇷 Felipe Meligeni Alves (quarterfinals)

• # 🇻🇪 Luis David Martínez / Gonçalo Oliveira (semifinals)

• # 🇲🇽 Hans Hach Verdugo / 🇲🇽 Miguel Ángel Reyes-Varela (final)

• # 🇺🇸 Evan King / 🇺🇸 Max Schnur (champions)