2021 Chile Open

The 2021 Chile Open (also known as the Chile Dove Men+Care Open for sponsorship reasons) was a men's tennis tournament played on outdoor clay courts. It was the 23rd edition of the Chile Open, and part of the ATP 250 of the 2021 ATP Tour. It took place in Santiago, Chile from 8 through 14 March 2021.

Singles

 *  Cristian Garín def. 🇦🇷 Facundo Bagnis, 6–4, 6–7(3–7), 7–5

Doubles

 * 🇮🇹 Simone Bolelli / 🇦🇷 Máximo González def. 🇦🇷 Federico Delbonis / 🇪🇸 Jaume Munar, 7–6(7–4), 6–4

Seeds

 * Rankings are as of March 1, 2021.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇦🇷 Juan Manuel Cerúndolo
 * Nicolás Jarry
 * Gonzalo Lama

The following player received special exemption into the singles main draw:
 * 🇦🇷 Francisco Cerúndolo

The following players received entry from the qualifying draw:
 * 🇦🇷 Sebastián Báez
 * Holger Rune
 * Alejandro Tabilo
 * 🇵🇪 Juan Pablo Varillas

Withdrawals

 * 🇮🇹 Fabio Fognini → replaced by 🇪🇸 Jaume Munar
 * 🇷🇸 Miomir Kecmanović → replaced by 🇸🇰 Andrej Martin
 * 🇩🇪 Dominik Koepfer → replaced by 🇨🇴 Daniel Elahi Galán
 * 🇦🇷 Juan Ignacio Londero → replaced by 🇦🇷 Facundo Bagnis
 * 🇪🇸 Pedro Martínez → replaced by 🇩🇪 Daniel Altmaier
 * 🇧🇷 Thiago Monteiro → replaced by 🇸🇰 Jozef Kovalík
 * 🇦🇷 Guido Pella → replaced by Pedro Sousa

Seeds

 * 1 Rankings are as of March 1, 2021

Other entrants
The following pairs received wildcards into the doubles main draw:
 * Marcelo Tomás Barrios Vera / Alejandro Tabilo
 * Nicolás Jarry / 🇦🇷 Leonardo Mayer

Withdrawals

 * Before the tournament
 * 🇦🇷 Federico Delbonis / 🇦🇷 Juan Ignacio Londero → replaced by 🇦🇷 Federico Delbonis / 🇪🇸 Jaume Munar