2021 Cleveland Open – Doubles

Treat Huey and Nathaniel Lammons were the defending champions but only Huey chose to defend his title, partnering Sem Verbeek. Huey lost in the quarterfinals to Emilio Gómez and Roberto Quiroz.

Robert Galloway and Alex Lawson won the title after defeating Evan King and Hunter Reese 7–5, 6–7(5–7), [11–9] in the final.

Seeds
• # Treat Huey / Sem Verbeek (quarterfinals)

• # 🇺🇸 Robert Galloway / 🇺🇸 Alex Lawson (champions)

• # 🇺🇸 Evan King / 🇺🇸 Hunter Reese (final)

• # 🇺🇸 Dennis Novikov / Ante Pavić (first round)