2021 Cruzeiro Esporte Clube season

The 2021 season was the 100th in the Cruzeiro Esporte Clube's existence.

Along with the Campeonato Brasileiro Série B, the club also competed in the Campeonato Mineiro and in the Copa do Brasil.

Squad information
Last updated on 9 October.

Transfers and loans
Last updated on 24 June.

Copa do Brasil
The drawn for the first stage was held on 2 March.

Appearances
Players with no appearances not included in the list.

Goalscorers
Includes all competitive matches. .

Assists
Includes all competitive matches. Not all goals have an assist. .

Clean sheets
Includes all competitive matches. .

Disciplinary record
Includes all competitive matches. .