2021 Delray Beach Open – Doubles

Bob and Mike Bryan were the two-time defending champions, but they retired in August 2020 so they did not defend their titles. Ariel Behar and Gonzalo Escobar won the title, defeating Christian and Ryan Harrison in the final, 6–7(5–7), 7–6(7–4), [10–4].

Seeds
• # Marcelo Arévalo / Jean-Julien Rojer (first round)

• # 🇳🇿 Marcus Daniell / 🇦🇹 Philipp Oswald (first round)

• # 🇧🇷 Marcelo Demoliner / 🇲🇽 Santiago González (first round)

• # 🇬🇧 Luke Bambridge / 🇬🇧 Dominic Inglot (first round)