2021 FINA World Swimming Championships (25 m) – Women's 4 × 100 metre freestyle relay

The Women's 4 × 100 metre freestyle relay competition of the 2021 FINA World Swimming Championships (25 m) was held on 16 December 2021.

Records
Prior to the competition, the existing world and championship records were as follows.

Heats
The heats were started at 12:18.

Final
The final will be held at 19:47.