2021 Gran Canaria Challenger II – Singles

This was the second edition of the tournament in the 2021 tennis season. Enzo Couacaud was the defending champion but lost in the second round to Alex Molčan.

Carlos Gimeno Valero won the title after defeating Kimmer Coppejans 6–4, 6–2 in the final.

Seeds
• # 🇪🇸 Carlos Alcaraz (second round)

• # 🇮🇹 Federico Gaio (second round)

• # 🇷🇸 Nikola Milojević (second round)

• # 🇷🇸 Danilo Petrović (first round, retired)

• # 🇮🇹 Lorenzo Giustino (first round)

• # 🇮🇹 Alessandro Giannessi (quarterfinals)

• # 🇸🇰 Filip Horanský (second round)

• # 🇧🇪 Kimmer Coppejans (final)