2021 Great Ocean Road Open – Singles

The Great Ocean Road Open was a new addition to the ATP Tour in 2021.

Jannik Sinner won the title, defeating Stefano Travaglia in the final, 7–6(7–4), 6–4. He saved a match point against Karen Khachanov in the semifinal.

Seeds
The top eight seeds received a bye into the second round.

🇧🇪 David Goffin (second round) 🇷🇺 Karen Khachanov (semifinals) 🇵🇱 Hubert Hurkacz (quarterfinals) 🇮🇹 Jannik Sinner (champion) Nikoloz Basilashvili (second round) 🇺🇸 Reilly Opelka (third round) 🇷🇸 Miomir Kecmanović (quarterfinals) 🇰🇿 Alexander Bublik (third round) 🇺🇸 Tennys Sandgren (second round) 🇺🇸 Sam Querrey (second round) 🇦🇺 Jordan Thompson (quarterfinals) 🇷🇸 Laslo Đere (first round) Aljaž Bedene (third round) 🇪🇸 Pablo Andújar (first round) 🇨🇦 Vasek Pospisil (withdrew) 🇪🇸 Feliciano López (first round)