2021 ITF Women's World Tennis Tour – Bellinzona – Singles

This was the first edition of the tournament.

Julia Grabher won the title, defeating Lucia Bronzetti in the final, 6–2, 6–3.

Seeds
All seeds receive a bye into the second round. • # 🇫🇷 Océane Dodin (second round)

• # 🇺🇦 Katarina Zavatska (third round, retired)

• # 🇨🇳 Wang Xiyu (second round)

• # 🇷🇴 Elena-Gabriela Ruse (third round)

• # 🇺🇦 Anhelina Kalinina (second round)

• # 🇹🇷 Çağla Büyükakçay (second round)

• # 🇩🇪 Antonia Lottner (second round)

• # 🇩🇪 Mona Barthel (quarterfinals)

• # 🇯🇵 Yuki Naito (second round)

• # 🇨🇳 Lu Jiajing (second round)

• # 🇮🇹 Martina Di Giuseppe (second round)

• # 🇷🇴 Laura Ioana Paar (second round)

• # Jana Fett (quarterfinals)

• # 🇰🇷 Han Na-lae (second round)

• # 🇧🇬 Isabella Shinikova (second round)

• # 🇨🇦 Rebecca Marino (second round)