2021 Internationaux Féminins de la Vienne – Singles

Nina Stojanović was the defending champion but chose to compete at the 2021 Torneig Internacional Els Gorchs instead.

Chloé Paquet won the title, defeating Simona Waltert in the final, 6–4, 6–3.

Seeds
• # 🇫🇷 Océane Dodin (quarterfinals)

• # 🇫🇷 Harmony Tan (semifinals, retired)

• # 🇭🇺 Tímea Babos (first round)

• # 🇫🇷 Chloé Paquet (champion)

• # 🇫🇷 Amandine Hesse (second round, retired)

• # Mariam Bolkvadze (quarterfinals)

• # 🇺🇦 Daria Snigur (second round)

• # 🇦🇹 Julia Grabher (first round)