2021 Internationaux de Tennis de Vendée

The 2021 Internationaux de Tennis de Vendée was a professional tennis tournament played on hard courts. It was the eighth edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Mouilleron-le-Captif, France between 4 and 10 October 2021.

Seeds

 * 1 Rankings are as of 27 September 2021.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇫🇷 Arthur Fils
 * 🇫🇷 Kyrian Jacquet
 * 🇫🇷 Harold Mayot

The following player received entry into the singles main draw as an alternate:
 * 🇫🇷 Constant Lestienne

The following players received entry from the qualifying draw:
 * 🇧🇪 Zizou Bergs
 * 🇫🇷 Titouan Droguet
 * 🇷🇺 Evgeny Karlovskiy
 * 🇩🇪 Mats Rosenkranz

The following player received entry as a lucky loser:
 * 🇫🇷 Kenny de Schepper

Singles

 * 🇨🇿 Jiří Veselý def. 🇸🇰 Norbert Gombos 6–4, 6–4.

Doubles

 * 🇫🇷 Jonathan Eysseric / 🇫🇷 Quentin Halys def. David Pel / 🇵🇰 Aisam-ul-Haq Qureshi 4–6, 7–6(7–5), [10–8].