2021 Internazionali di Tennis Città di Verona – Singles

This was the first edition of the tournament.

Holger Rune won the title after defeating Nino Serdarušić 6–4, 6–2 in the final.

Seeds
• # 🇪🇸 Carlos Taberner (semifinals)

• # 🇰🇿 Dmitry Popko (quarterfinals)

• # 🇮🇹 Paolo Lorenzi (second round)

• # Holger Rune (champion)

• # 🇬🇧 Jay Clarke (semifinals)

• # 🇫🇷 Maxime Janvier (quarterfinals)

• # 🇮🇹 Lorenzo Giustino (first round)

• # Gastão Elias (quarterfinals)