2021 JC Ferrero Challenger Open – Singles

Carlos Alcaraz was the defending champion but chose not to defend his title.

Constant Lestienne won the title after defeating Hugo Grenier 6–4, 6–3 in the final.

Seeds
• # 🇪🇸 Feliciano López (second round)

• # 🇪🇸 Fernando Verdasco (second round)

• # 🇩🇪 Oscar Otte (semifinals)

• # 🇫🇷 Quentin Halys (first round)

• # 🇰🇿 Dmitry Popko (first round)

• # 🇵🇱 Kacper Żuk (second round)

• # 🇪🇸 Mario Vilella Martínez (second round)

• # João Sousa (semifinals)