2021 Kilkenny Senior Hurling Championship

The 2021 Kilkenny Senior Hurling Championship was the 127th staging of the Kilkenny Senior Hurling Championship since its establishment by the Kilkenny County Board in 1887. The championship began on 2 October 2021 and ended on 7 November 2021.

Ballyhale Shamrocks entered the championship as the defending champions. Rower-Inistioge were relegated from the championship after being beaten in a playoff by Erin's Own.

The final was played on 7 November 2021 at UPMC Nowlan Park in Kilkenny, between Ballyhale Shamrocks and O'Loughlin Gaels, in what was their first meeting in a final in five years. Ballyhale Shamrocks won the match by 3–19 to 3–15 to claim their 19th championship title overall and a fourth title in succession.

T. J. Reid was the championship's top scorer with 1-31.

To Championship
Promoted from the Kilkenny Intermediate Hurling Championship
 * Lisdowney

From Championship
Relegated to the Kilkenny Intermediate Hurling Championship
 * Danesfort

Top scorers

 * Overall


 * In a single game