2021 Kuchyně Gorenje Prague Open

The 2021 Kuchyně Gorenje Prague Open was a professional women's tennis tournament played on outdoor clay courts. It was the eighth edition of the tournament which was part of the 2021 ITF Women's World Tennis Tour. It took place in Prague, Czech Republic between 30 August and 5 September 2021.

Seeds

 * 1 Rankings are as of 23 August 2021.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇨🇿 Sára Bejlek
 * 🇨🇿 Monika Kilnarová
 * 🇨🇿 Linda Nosková
 * 🇨🇿 Darja Viďmanová

The following players received entry from the qualifying draw:
 * 🇦🇺 Alexandra Bozovic
 * Tina Cvetkovič
 * 🇩🇪 Anna Gabric
 * 🇮🇱 Lina Glushko
 * 🇯🇵 Mana Kawamura
 * 🇫🇷 Alice Ramé
 * 🇨🇿 Tereza Smitková
 * 🇺🇦 Valeriya Strakhova

Singles

 * 🇵🇱 Magdalena Fręch def. 🇨🇿 Tereza Smitková, 6–2, 6–1

Doubles

 * 🇨🇿 Miriam Kolodziejová / 🇨🇿 Jesika Malečková def. 🇯🇵 Kanako Morisaki / 🇯🇵 Erika Sema, 6–3, 1–6, [10–2]