2021 Ladies Open Lausanne

The 2021 Ladies Open Lausanne was a women's tennis tournament played on outdoor clay courts. It was the 28th edition of the Ladies Open Lausanne, and part of the 250 category of the 2021 WTA Tour. It took place at Tennis Club Stade-Lausanne in Lausanne, Switzerland, from 12 through 18 July 2021.

Singles

 * Tamara Zidanšek defeated 🇫🇷 Clara Burel, 4–6, 7–6(7–5), 6–1

This was Zidanšek's maiden WTA Tour singles title.

Doubles

 * Susan Bandecchi / Simona Waltert defeated 🇳🇴 Ulrikke Eikeri /  Valentini Grammatikopoulou, 6–3, 6–7(3–7), [10–5]

Seeds

 * 1 Rankings are as of 28 June 2021.

Other entrants
The following players received wildcards into the main draw:
 * 🇺🇸 Alycia Parks
 * Tess Sugnaux
 * Simona Waltert

The following player received entry using a protected ranking:
 * 🇷🇴 Alexandra Dulgheru
 * 🇱🇺 Mandy Minella

The following players received entry from the qualifying draw:
 * 🇮🇹 Lucia Bronzetti
 * 🇳🇴 Ulrikke Eikeri
 * Valentini Grammatikopoulou
 * 🇦🇺 Astra Sharma

Withdrawals

 * Before the tournament
 * 🇷🇴 Sorana Cîrstea → replaced by 🇧🇪 Maryna Zanevska
 * 🇫🇷 Alizé Cornet → replaced by 🇺🇸 Francesca Di Lorenzo
 * 🇵🇱 Katarzyna Kawa → replaced by 🇷🇴 Alexandra Dulgheru
 * 🇷🇺 Liudmila Samsonova → replaced by 🇫🇷 Clara Burel
 * 🇺🇸 Sloane Stephens → replaced by 🇱🇺 Mandy Minella
 * 🇮🇹 Martina Trevisan → replaced by 🇷🇺 Marina Melnikova

Seeds

 * 1 Rankings are as of 28 June 2021.

Other entrants
The following pairs received wildcards into the doubles main draw:
 * Susan Bandecchi / Simona Waltert
 * 🇫🇷 Carole Monnet / 🇺🇸 Gabriella Price

The following pair received entry as alternates:
 * 🇷🇴 Elena Bogdan / 🇷🇴 Alexandra Dulgheru

Withdrawals

 * Before the tournament
 * 🇺🇿 Akgul Amanmuradova / 🇷🇺 Valentina Ivakhnenko → replaced by 🇷🇺 Valentina Ivakhnenko / 🇨🇿 Jesika Malečková
 * 🇷🇺 Anna Blinkova / 🇩🇪 Anna-Lena Friedsam → replaced by 🇷🇴 Elena Bogdan / 🇷🇴 Alexandra Dulgheru
 * 🇩🇪 Vivian Heisen / Oksana Kalashnikova → replaced by 🇱🇺 Mandy Minella /  Stefanie Vögele
 * During the tournament
 * 🇵🇱 Katarzyna Piter / Arantxa Rus
 * Jil Teichmann / Tamara Zidanšek
 * 🇺🇸 Francesca Di Lorenzo / 🇦🇺 Astra Sharma