2021 Lima Challenger – Singles

Daniel Elahi Galán was the defending champion, but chose not to defend his title.

Hugo Dellien won the title after defeating Camilo Ugo Carabelli 6–3, 7–5 in the final.

Seeds
• # 🇦🇷 Francisco Cerúndolo (first round)

• # 🇦🇷 Juan Manuel Cerúndolo (quarterfinals, retired)

• # 🇩🇪 Daniel Altmaier (second round)

• # 🇵🇪 Juan Pablo Varillas (second round)

• # 🇧🇴 Hugo Dellien (champion)

• # 🇦🇷 Renzo Olivo (quarterfinals)

• # 🇦🇷 Juan Pablo Ficovich (first round)

• # 🇦🇷 Camilo Ugo Carabelli (final)