2021 Los Cabos Open

The 2021 Los Cabos Open (also known as the Mifel Open for sponsorship reasons) was an ATP tennis tournament played on outdoor hard court. It was the 5th edition of the tournament, and part of the ATP Tour 250 series of the 2021 ATP Tour. It took place in Los Cabos, Mexico from 19 July through 25 July 2021.

Singles

 * 🇬🇧 Cameron Norrie def. 🇺🇸 Brandon Nakashima 6–2, 6–2.

Doubles

 * 🇲🇽 Hans Hach Verdugo / 🇺🇸 John Isner def. 🇺🇸 Hunter Reese / Sem Verbeek 5–7, 6–2, [10–4].

Prize money

 * per team

Seeds

 * Rankings are as of July 12, 2021.

Other entrants
The following players received wildcards into the main draw:
 * Ivo Karlović
 * 🇦🇺 Thanasi Kokkinakis
 * 🇲🇽 Gerardo López Villaseñor

The following players received entry from the qualifying draw:
 * 🇦🇺 Matthew Ebden
 * 🇺🇸 Ernesto Escobedo
 * 🇨🇴 Nicolás Mejía
 * 🇺🇸 Alexander Sarkissian

Withdrawals

 * Kevin Anderson → replaced by 🇸🇪 Elias Ymer
 * 🇱🇹 Ričardas Berankis → replaced by 🇦🇹 Jurij Rodionov
 * 🇧🇬 Grigor Dimitrov → replaced by 🇺🇸 Brandon Nakashima
 * 🇦🇺 James Duckworth → replaced by 🇯🇵 Yasutaka Uchiyama
 * 🇨🇴 Daniel Elahi Galán → replaced by 🇪🇨 Emilio Gómez
 * 🇧🇾 Egor Gerasimov → replaced by 🇷🇺 Evgeny Donskoy
 * 🇧🇾 Ilya Ivashka → replaced by 🇦🇹 Sebastian Ofner
 * 🇺🇸 Sebastian Korda → replaced by 🇩🇪 Peter Gojowczyk
 * 🇫🇷 Adrian Mannarino → replaced by 🇺🇸 J. J. Wolf
 * 🇦🇷 Guido Pella → replaced by 🇦🇺 Alex Bolt

Retirements

 * 🇦🇹 Jurij Rodionov

Seeds

 * 1 Rankings are as of 12 July 2021.

Other entrants
The following pairs received wildcards into the doubles main draw:
 * 🇺🇸 Ernesto Escobedo / 🇲🇽 Luis Patiño
 * 🇺🇸 Mackenzie McDonald / 🇺🇸 Sam Querrey

Withdrawals

 * Before the tournament
 * Marcelo Arévalo / 🇲🇽 Miguel Ángel Reyes-Varela → replaced by 🇫🇮 Harri Heliövaara / 🇲🇽 Miguel Ángel Reyes-Varela
 * Ričardas Berankis / 🇫🇮 Harri Heliövaara → replaced by 🇮🇳 Sriram Balaji / Luca Margaroli
 * 🇬🇧 Lloyd Glasspool / 🇬🇧 Cameron Norrie → replaced by 🇷🇺 Evgeny Donskoy / 🇺🇦 Illya Marchenko
 * 🇦🇺 Matt Reid / 🇦🇺 Jordan Thompson → replaced by 🇦🇺 Alex Bolt / 🇦🇺 Jordan Thompson
 * During the tournament
 * 🇦🇺 Alex Bolt / 🇦🇺 Jordan Thompson