2021 Massachusetts State Collegiate Athletic Conference football season

The 2021 Massachusetts State Collegiate Athletic Conference football season was the season of college football played by the nine member schools of the Massachusetts State Collegiate Athletic Conference (MASCAC) as part of the 2021 NCAA Division III football season. The Framingham State Rams were conference champions; compiling perfect 8–0 records against conference opponents.

Framingham State
The 2021 Framingham State Rams football team represented Framingham State University as a member of the Massachusetts State Collegiate Athletic Conference (MASCAC) during the 2021 NCAA Division III football season. The Rams, led by 14th-year head coach Tom Kelley, played their home games at Bowditch Field in Framingham, Massachusetts.

UMass Dartmouth
The 2021 UMass Dartmouth Corsairs football team represented the University of Massachusetts Dartmouth as a member of the Massachusetts State Collegiate Athletic Conference (MASCAC) during the 2021 NCAA Division III football season. The Corsairs, led by 15th-year head coach Mark Robichaud, played their home games at Cressy Field in Dartmouth, Massachusetts.

Bridgewater State
The 2021 Bridgewater State Bears football team represented Bridgewater State University as a member of the Massachusetts State Collegiate Athletic Conference (MASCAC) during the 2021 NCAA Division III football season. The Bears, led by 6th-year head coach Joe Verria, played their home games at Swenson Field in Bridgewater, Massachusetts.

Plymouth State
The 2021 Plymouth State Panthers football team represented Plymouth State University as a member of the Massachusetts State Collegiate Athletic Conference (MASCAC) during the 2021 NCAA Division III football season. The Panthers, led by 18th-year head coach Paul Castonia, played their home games at Panther Field in Plymouth, New Hampshire.

Western Connecticut
The 2021 Western Connecticut Colonials football team represented Western Connecticut State University as a member of the Massachusetts State Collegiate Athletic Conference (MASCAC) during the 2021 NCAA Division III football season. The Colonials, led by 9th-year head coach Joe Loth, played their home games at the WAC in Danbury, Connecticut.

Massachusetts Maritime
The 2021 Massachusetts Maritime Buccaneers football team represented Massachusetts Maritime Academy as a member of the Massachusetts State Collegiate Athletic Conference (MASCAC) during the 2021 NCAA Division III football season. The Buccaneers, led by 17th-year head coach Jeremy Cameron, played their home games at Clean Harbors Stadium in Buzzards Bay, Massachusetts.

Worcester State
The 2021 Worcester State Lancers football team represented Worcester State University as a member of the Massachusetts State Collegiate Athletic Conference (MASCAC) during the 2021 NCAA Division III football season. The Lancers, led by 2nd-year head coach Adam Peloquin, played their home games at John F. Coughlin Field in Worcester, Massachusetts.

Westfield State
The 2021 Westfield State Owls football team represented Westfield State University as a member of the Massachusetts State Collegiate Athletic Conference (MASCAC) during the 2021 NCAA Division III football season. The Owls, led by 8th-year head coach Pete Kowalski, played their home games at Alumni Field in Westfield, Massachusetts.

Fitchburg State
The 2021 Fitchburg State Falcons football team represented Fitchburg State University as a member of the Massachusetts State Collegiate Athletic Conference (MASCAC) during the 2021 NCAA Division III football season. The Falcons, led by 1st-year head coach Scott Sperone, played their home games at Elliot Field in Fitchburg, Massachusetts.

All-conference team
Offensive Player of the Year – Devaun Ford, Framingham State, running back

Defensive Player of the Year – Joshua Onujiogu, Framingham State, defensive end

Offensive Lineman of the Year – Bryan Lawton, Framingham State, guard

Offensive Rookie of the Year – Dante Aviles-Santos, UMass Dartmouth, quarterback

Defensive Rookie of the Year – Dylan DeWolfe, Framingham State, linebacker

Coach of the Year – Tom Kelley, Framingham State