2021 Moselle Open – Singles

Jo-Wilfried Tsonga was the reigning champion from when the tournament was last held in 2019, but chose not to participate this year.

Hubert Hurkacz won the title, defeating Pablo Carreño Busta in the final, 7–6(7–2), 6–3.

Seeds
The top four seeds received a bye into the second round. • #🇵🇱 Hubert Hurkacz (champion)

• #🇪🇸 Pablo Carreño Busta (final)

• #🇫🇷 Gaël Monfils (semifinals)

• #🇦🇺 Alex de Minaur (second round)

• #🇮🇹 Lorenzo Sonego (second round)

• #🇫🇷 Ugo Humbert (first round)

• #🇷🇺 Karen Khachanov (second round)

• # Nikoloz Basilashvili (quarterfinals)

Seeds
• # 🇸🇪 Mikael Ymer (moved to the main draw)

• # 🇩🇪 Peter Gojowczyk (qualified)

• # 🇩🇪 Philipp Kohlschreiber (qualifying competition, lucky loser)

• # 🇪🇸 Bernabé Zapata Miralles (qualifying competition, lucky loser)

• # Holger Rune (qualified)

• # 🇫🇷 Antoine Hoang (qualifying competition, lucky loser)

• # 🇮🇹 Federico Gaio (first round)

• # 🇫🇷 Quentin Halys (first round)

Qualifiers
• # 🇨🇦 Brayden Schnur

• # 🇩🇪 Peter Gojowczyk

• # Holger Rune

• # 🇫🇷 Alexandre Müller

Lucky losers
• # 🇩🇪 Philipp Kohlschreiber

• # 🇪🇸 Bernabé Zapata Miralles

• # 🇫🇷 Antoine Hoang