2021 Murray River Open

The 2021 Murray River Open was a tournament on the 2021 ATP Tour. It was played on outdoor hard courts in Melbourne, Australia. It was organised as a lead-up tournament to the 2021 Australian Open, and was held at the same venue, due to other tournaments in Australia being cancelled as a result from the COVID-19 pandemic. This tournament took place simultaneously with the 2021 Great Ocean Road Open and the 2021 ATP Cup.

Prize money

 * per team

Seeds

 * 1 Rankings are as of January 25, 2021

Other entrants
The following players received wildcards into the main draw:
 * 🇦🇺 Andrew Harris
 * 🇦🇺 Jason Kubler
 * 🇦🇺 Blake Mott
 * 🇦🇺 Li Tu

The following players have been accepted directly into the main draw using a protected or a special ranking:
 * 🇦🇺 Thanasi Kokkinakis

The following player received entry as an alternate:
 * 🇦🇺 Harry Bourchier

Withdrawals

 * Before the tournament
 * 🇪🇸 Alejandro Davidovich Fokina → replaced by 🇯🇵 Yūichi Sugita
 * João Sousa → replaced by 🇦🇺 James Duckworth
 * 🇦🇺 Bernard Tomic → replaced by 🇦🇺 Harry Bourchier
 * During the tournament
 * Stan Wawrinka

Retirements

 * 🇨🇿 Jiří Veselý

Seeds

 * Rankings are as of January 25, 2021.

Other entrants
The following pairs received wildcards into the doubles main draw:
 * 🇦🇺 James Duckworth / 🇦🇺 Marc Polmans
 * 🇦🇺 Andrew Harris / 🇦🇺 Alexei Popyrin

The following pair received entry using a protected ranking:
 * 🇺🇸 Mackenzie McDonald / 🇺🇸 Tommy Paul

Singles

 * 🇬🇧 Dan Evans def. 🇨🇦 Félix Auger-Aliassime, 6–2, 6–3

Doubles

 * Nikola Mektić / Mate Pavić def. 🇫🇷 Jérémy Chardy / 🇫🇷 Fabrice Martin, 7–6(7–2), 6–3