2021 Pekao Szczecin Open – Singles

Jozef Kovalík was the defending champion but chose not to defend his title.

Zdeněk Kolář won the title after defeating Kamil Majchrzak 7–6(7–4), 7–5 in the final.

Seeds
• # 🇪🇸 Albert Ramos Viñolas (first round)

• # 🇪🇸 Pablo Andújar (second round)

• # 🇪🇸 Pedro Martínez (withdrew)

• # 🇮🇹 Marco Cecchinato (second round)

• # 🇨🇿 Jiří Veselý (first round)

• # 🇧🇷 Thiago Monteiro (second round)

• # 🇪🇸 Roberto Carballés Baena (second round)

• # 🇮🇹 Stefano Travaglia (second round)