2021 San Diego Open – Doubles

This was the first edition of the tournament, which was primarily organized to compensate for the cancellation of Asian tournaments in 2021 due to the COVID-19 pandemic.

Joe Salisbury and Neal Skupski won the title, defeating John Peers and Filip Polášek in the final, 7–6(7–2), 3–6, [10–5].

Seeds
• # 🇬🇧 Joe Salisbury / 🇬🇧 Neal Skupski (champions)

• # 🇬🇧 Jamie Murray / 🇧🇷 Bruno Soares (first round)

• # 🇦🇺 John Peers / 🇸🇰 Filip Polášek (final)

• # 🇮🇹 Simone Bolelli / 🇦🇷 Máximo González (quarterfinals)