2021 Sardegna Open

The 2021 Sardegna Open was a tennis tournament on the 2021 ATP Tour. It was played on outdoor clay courts in Cagliari, Sardinia, Italy. It was organised with a single-year licence in 2021, and was held at Tennis Club Cagliari from April 5 to 11, 2021.

The Italian 250 debuted October 2020 as a response to the COVID-19 pandemic to increase earning opportunities for players. It returned to Sardegna in 2021 and opened the red-clay season in Europe.

Singles

 * 🇮🇹 Lorenzo Sonego def. 🇷🇸 Laslo Đere, 2–6, 7–6(7–5), 6–4

Doubles

 * 🇮🇹 Lorenzo Sonego / 🇮🇹 Andrea Vavassori def. 🇮🇹 Simone Bolelli / 🇦🇷 Andrés Molteni, 6–3, 6–4

Prize money

 * per team

Seeds

 * 1 Rankings are as of March 22, 2021

Other entrants
The following players received wildcards into the main draw:
 * 🇮🇹 Federico Gaio
 * 🇮🇹 Thomas Fabbiano
 * 🇮🇹 Giulio Zeppieri

The following players received entry from the qualifying draw:
 * 🇬🇧 Liam Broady
 * Marc-Andrea Hüsler
 * 🇸🇰 Jozef Kovalík
 * 🇮🇳 Sumit Nagal

Withdrawals

 * Before the tournament
 * 🇫🇷 Jérémy Chardy → replaced by João Sousa
 * Cristian Garín → replaced by 🇦🇷 Federico Coria
 * 🇷🇺 Aslan Karatsev → replaced by 🇮🇹 Lorenzo Musetti
 * 🇧🇷 Thiago Monteiro → replaced by 🇸🇰 Andrej Martin
 * 🇪🇸 Fernando Verdasco → replaced by 🇩🇪 Yannick Hanfmann

Seeds

 * Rankings are as of March 22, 2021.

Other entrants
The following pairs received wildcards into the doubles main draw:
 * 🇮🇹 Jacopo Berrettini / 🇮🇹 Matteo Berrettini
 * 🇮🇹 Andrea Pellegrino / 🇮🇹 Giulio Zeppieri

The following pair received entry using a protected ranking:
 * 🇨🇿 Roman Jebavý / 🇸🇰 Igor Zelenay

Withdrawals

 * Before the tournament
 * 🇺🇸 Rajeev Ram / 🇬🇧 Joe Salisbury → replaced by 🇫🇮 Harri Heliövaara / 🇺🇦 Denys Molchanov
 * 🇬🇧 Jonny O'Mara / 🇬🇧 Ken Skupski → replaced by 🇬🇧 Lloyd Glasspool / 🇬🇧 Jonny O'Mara
 * During the tournament
 * 🇬🇧 Dan Evans / 🇦🇷 Federico Coria