2021 Southeastern Conference softball season

The 2021 SEC softball season began play Thursday, February 11, and conference play began on Thursday, March 11. The 2021 Southeastern Conference softball tournament was May 11–13 at Rhoads Stadium in Tuscaloosa, Alabama. Alabama played Florida in the tournament final, winning by a score of 4–0. Vanderbilt University is the only full member of the Southeastern Conference to not sponsor a softball program.

SEC preseason poll
The head coaches SEC preseason poll was released on January 28, 2021. Each head coach votes on a scale of 12 points for first place down to 1 point for last place, 12th. Each coach only votes for 12 teams, since they can not vote for their own team. Alabama was picked to finish 1st, with nine 1st place votes. LSU was 2nd with two 1st place votes, Florida 3rd with one, and Tennessee 4th with the remaining one 1st place vote.

Record vs. conference opponents
Tiebrkrs: FLA>ARK ALA common. LSU>KEN hd–hd. UGA>AUB MIZZ common.

National rankings
At some time during the season, all thirteen SEC softball teams were ranked in the top 25 of two of the three major polls. The final rankings had 7 or 8 teams in the top 25. Twelve teams made the NCAA Tournament.
 * Alabama, for 15 weeks straight was, and finished, in the top 5, having won the SEC softball tournament and made the semifinals of the Women's College World Series (WCWS).
 * Georgia was unranked and rose to 8th, being the only other SEC team to make the WCWS. Only eight teams nationwide made the WCWS.
 * Florida was in the top ten of every poll throughout the 2021 campaign. They made the championship game of the SEC tournament, losing to Alabama, and lost in their Super Regional to Georgia, just missing making the WCWS.
 * Arkansas also lost their Super Regional, also just missing out on the WCWS.
 * Missouri lost their Super Regional.
 * LSU lost their Super Regional.
 * Kentucky lost to Alabama in Alabama's Super Regional.
 * Tennessee lost their Regional 1–2.
 * South Carolina went 0–1 in the SEC tournament.
 * Mississippi State went 1–1 in the SEC tournament and went 2–2 losing in the finals of a Regional.
 * Ole Miss went 0–1 in the SEC tournament and also went 2–2 losing in the finals of a Regional.
 * Texas A&M went 0–1 in the SEC tournament and went 1–2 losing in the finals of a Regional.

NFCA/USA Today
See 2021 NCAA Division I softball rankings also.

D1Softball
See 2021 NCAA Division I softball rankings also.

ESPN/USA Softball Collegiate
See 2021 NCAA Division I softball rankings also.