2021 Split Open – Singles

Francisco Cerúndolo was the defending champion but chose not to defend his title.

Blaž Rola won the title after defeating Blaž Kavčič 2–6, 6–3, 6–2 in the final.

Seeds
• # Pedro Sousa (first round, retired)

• # 🇦🇺 Marc Polmans (first round)

• # 🇦🇹 Sebastian Ofner (first round)

• # 🇪🇬 Mohamed Safwat (first round)

• # 🇷🇸 Danilo Petrović (quarterfinals)

• # Blaž Rola (champion)

• # 🇧🇪 Kimmer Coppejans (second round)

• # 🇸🇰 Filip Horanský (first round)