2021 Split Open II – Singles

Blaž Rola was the defending champion but chose not to defend his title.

Kacper Żuk won the title after defeating Mathias Bourgue 6–4, 6–2 in the final.

Seeds
• # 🇫🇷 Grégoire Barrère (first round)

• # 🇦🇺 Marc Polmans (first round)

• # 🇫🇷 Hugo Gaston (second round)

• # 🇪🇬 Mohamed Safwat (first round)

• # 🇧🇪 Kimmer Coppejans (first round)

• # 🇮🇹 Lorenzo Giustino (first round)

• # 🇸🇰 Filip Horanský (second round)

• # 🇨🇦 Steven Diez (first round)