2021 WTA Argentina Open – Singles

This was the first edition of the tournament since 1987.

Anna Bondár won the title, defeating Diane Parry in the final, 6–3, 6–3.

Seeds
• # 🇪🇬 Mayar Sherif (semifinals)

• # 🇧🇷 Beatriz Haddad Maia (quarterfinals)

• # 🇭🇺 Anna Bondár (champion)

• # 🇷🇴 Irina Bara (quarterfinals)

• # 🇭🇺 Panna Udvardy (semifinals)

• # Ekaterine Gorgodze (quarterfinals)

• # 🇫🇷 Diane Parry (final)

• # Despina Papamichail (quarterfinals)

Seeds
• # 🇦🇷 Martina Capurro Taborda (qualified)

• # 🇧🇷 Rebeca Pereira (qualifying competition)

Qualifiers
• # 🇦🇷 Martina Capurro Taborda

• # 🇦🇷 Sol Faga

• # 🇦🇷 Luciana Moyano

• # 🇦🇷 María Victoria Burstein