2021 Wartburg Knights football team

The 2021 Wartburg Knights football team represented Wartburg College as a member of the American Rivers Conference (ARC) during the 2021 NCAA Division III football season. Led by first-year head coach Chris Winter, the Knights opened the season and Winters tenure with a win. They would open conference play with a win over Coe but would finish the season with an overall record of 7–3 and a mark of 6–2 in the ARC, placing second. The team played home games at Walston-Hoover Stadium in Waverly, Iowa.