2021 Wiesbaden Tennis Open

The 2021 Wiesbaden Tennis Open was a professional women's tennis tournament played on outdoor clay courts. It was the twelfth edition of the tournament which was part of the 2021 ITF Women's World Tennis Tour. It took place in Wiesbaden, Germany between 20 and 26 September 2021.

Seeds

 * 1 Rankings are as of 13 September 2021.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇩🇪 Mina Hodzic
 * 🇩🇪 Kathleen Kanev
 * 🇩🇪 Anna Klasen
 * 🇩🇪 Laura Isabel Putz

The following player received entry using a junior exempt:
 * 🇦🇩 Victoria Jiménez Kasintseva

The following players received entry from the qualifying draw:
 * Kamilla Bartone
 * 🇧🇦 Nefisa Berberović
 * 🇮🇹 Cristiana Ferrando
 * 🇲🇰 Lina Gjorcheska
 * Arianne Hartono
 * 🇩🇪 Lena Papadakis
 * 🇷🇴 Andreea Roșca
 * 🇩🇪 Stephanie Wagner

The following player received entry as a lucky loser:
 * 🇩🇪 Yana Morderger

Singles

 * 🇭🇺 Anna Bondár def. 🇫🇷 Clara Burel, 6–2, 6–4

Doubles

 * 🇭🇺 Anna Bondár / 🇧🇪 Lara Salden def. Arianne Hartono / 🇦🇺 Olivia Tjandramulia, 6–7(9–11), 6–2, [10–4]