2021 Winners Open – Singles

This was the first edition of the tournament.

Andrea Petkovic won her first title since 2015, defeating Mayar Sherif in the final, 6–1, 6–1. Sherif become the first Egyptian player to be in the final of WTA Tour tournament.

Seeds
• # 🇫🇷 Alizé Cornet (first round)

• # 🇩🇪 Andrea Petkovic (champion)

• # 🇷🇴 Ana Bogdan (second round)

• # 🇮🇹 Martina Trevisan (first round)

• # 🇷🇴 Elena-Gabriela Ruse (first round)

• # Kaja Juvan (second round)

• # 🇧🇬 Viktoriya Tomova (first round)

• # 🇸🇰 Kristína Kučová (quarterfinals)

Seeds
• #🇭🇺 Panna Udvardy (qualified)

• #🇭🇺 Anna Bondár (first round)

• #🇦🇷 Paula Ormaechea (qualified)

• # Jana Fett (qualified)

• #🇷🇴 Gabriela Talabă (qualifying competition)

• #🇧🇬 Isabella Shinikova (first round)

• # Daniela Seguel (first round)

• #🇧🇪 Marie Benoît (first round)

• #🇷🇴 Irina Fetecău (qualifying competition)

• #🇮🇹 Lucrezia Stefanini (qualifying competition)

• #🇮🇹 Jessica Pieri (first round)

• #🇲🇽 Ana Sofía Sánchez (qualifying competition)

Qualifiers
• #🇭🇺 Panna Udvardy

• #🇷🇸 Aleksandra Krunić

• #🇦🇷 Paula Ormaechea

• # Jana Fett

• #🇷🇴 Alexandra Dulgheru

• #🇦🇺 Seone Mendez