2021 World Athletics Relays – Women's 4 × 400 metres relay

The women's 4 × 400 metres relay at the 2021 World Athletics Relays was held at Silesian Stadium on 1 and 2 May.

Records
Prior to the competition, the records were as follows:

Heats
Qualification: First 2 of each heat (Q) plus the 2 fastest times (q) advanced to the final.