2022–23 AFC Wimbledon season

The 2022–23 season is the 21st season in the existence of AFC Wimbledon and the club's first season back in League Two since the 2015–16 season following their relegation from League One last season. In addition to the league, they will also compete in the 2022–23 FA Cup, the 2022–23 EFL Cup and the 2022–23 EFL Trophy.

Pre-season and friendlies
On 31 May, AFC Wimbledon announced their first four pre-season friendlies. A fifth friendly match was added, against Farnborough.

Matches
On 23 June, the league fixtures were announced.

FA Cup
AFC Wimbledon were drawn away to Weymouth in the first round.

EFL Cup
Wimbledon were drawn at home to Gillingham in the first round.

EFL Trophy
On 20 June, the initial Group stage draw was made, grouping AFC Wimbleon with Crawley Town and Portsmouth. Three days later, Aston Villa U21s joined Southern Group B. In the third round, the Dons were drawn away to Plymouth Argyle.