2022–23 Coppa Italia Serie C

The 2022–23 Coppa Italia Serie C was the 50th season of the Coppa Italia Serie C, the cup competition for Serie C clubs.

Padova were the defending champions having won their second title in April 2022 against Südtirol, with a 1–0 final score in the 2021-22 Coppa Italia Serie C final.

Group A (20 teams)

 * AlbinoLeffe
 * Arzignano
 * Feralpisalò
 * Juventus Next Gen
 * Lecco
 * Mantova
 * Novara
 * Padova
 * Pergolettese
 * Piacenza
 * Pordenone
 * Pro Patria
 * Pro Sesto
 * Pro Vercelli
 * Renate
 * Sangiuliano
 * Trento
 * Triestina
 * Vicenza
 * V. Verona

Group B (20 teams)

 * Alessandria
 * Ancona
 * Carrarese
 * Cesena
 * Fermana
 * Fiorenzuola
 * Gubbio
 * Imolese
 * Lucchese
 * Montevarchi
 * Olbia
 * Pontedera
 * Recanatese
 * Reggiana
 * Rimini
 * San Donato
 * Siena
 * Torres
 * Entella
 * Vis Pesaro

Group C (20 teams)

 * Cerignola
 * Avellino
 * Catanzaro
 * Crotone
 * Andria
 * Foggia
 * Gelbison
 * Giugliano
 * Juve Stabia
 * Latina
 * Messina
 * Monopoli
 * Monterosi
 * Pescara
 * Picerno
 * Potenza
 * Taranto
 * Turris
 * Francavilla
 * Viterbese

Format and seeding
The 60 teams in the 2022–23 Serie C entered the competition at various stages, as follows:


 * First phase (one-legged fixtures)
 * First round (one-legged): it is contested by the 56 teams who do not participate in the Coppa Italia.
 * Second round (one-legged): it is contested by the 28 winners of the first round and the four teams that participate in Coppa Italia.
 * Second phase
 * Round of 16 (one-legged): it is contested by the 16 winners of the second round.
 * Quarter-finals (one-legged)
 * Semi-finals (two-legged)
 * Final (two-legged)