2022–23 EHF European League knockout stage

The 2022–23 EHF European League knockout stage began on 21 March with the Last 16 and ended on 28 May with the final at the Campushalle in Flensburg, Germany, to decide the winners of the 2022–23 EHF European League.

Format
In the Last 16, the 16 teams ranked 1st–4th in the group stage play against each other in two-legged home-and-away matches. The eight winning teams advance to the quarterfinals, for another round of two-legged home-and-away matches. The four quarterfinal winners qualify for the final four tournament at the Campushalle (formerly Flens-Arena) in Flensburg, Germany.

Pairings
 The pairings for the last 16 and the quarterfinals are based on group stage standings, according to the following bracket. This assures teams from the same group can only play each other again in the final four.



Last 16
 The last 16 first legs were played 21 March 2023, while the second legs followed on 28 March 2023.


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Quarterfinals
 The quarterfinals first legs were played 11 April 2023, while the second legs followed on 18 April 2023.


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Final four
The final four was held at the Campushalle in Flensburg, Germany on 27 and 28 May 2023. The draw for the semifinals was held on 20 April 2023. 

Bracket
 

Final
 