2022–23 East Carolina Pirates women's basketball team

The 2022–23 East Carolina Pirates women's basketball team represented East Carolina University during the 2022–23 NCAA Division I women's basketball season. The Pirates, led by fourth-year head coach Kim McNeill, played their home games at Williams Arena at Minges Coliseum and were ninth-year members of the American Athletic Conference (AAC).

Previous season
The Pirates finished the 2021–22 season 11–18, 4–11 in AAC play, to finish in a tie for last place. They lost in the first round of the AAC women's tournament to Memphis.

Departures
Due to COVID-19 disruptions throughout NCAA sports in 2020–21, the NCAA announced that the 2020–21 season would not count against the athletic eligibility of any individual involved in an NCAA winter sport, including women's basketball. This meant that all seniors in 2020–21 had the option to return for 2021–22.

Media
All Pirates home and road games will have a video stream on ESPN+.

Schedule and results
!colspan=12 style=| Non-conference regular season

!colspan=12 style=| AAC regular season

!colspan=12 style=|AAC women's tournament

!colspan=12 style=|NCAA tournament

Rankings
 * The preseason and week 1 polls were the same. ^Coaches did not release a week 2 poll.