2022–23 US Lecce season

The 2022–23 season was the 96th season in the history of U.S. Lecce and the club's first season back in the top flight since 2020. The club participated in Serie A and the Coppa Italia.

Pre-season and friendlies
Lecce started training in Folgaria on 30 June.

Matches
The league fixtures were announced on 24 June 2022.