2022 ATP Lyon Open

The 2022 ATP Lyon Open (also known as the Open Parc Auvergne-Rhône-Alpes Lyon) was a men's tennis tournament played on outdoor clay courts. It was the 5th edition of the Lyon Open and part of the ATP Tour 250 series of the 2022 ATP Tour. It took place in the city of Lyon, France, from 15 May through 21 May 2022. First-seeded Cameron Norrie won the singles title.

Singles

 * 🇬🇧 Cameron Norrie defeated 🇸🇰 Alex Molčan, 6–3, 6–7(3–7), 6–1

Doubles

 * Ivan Dodig / 🇺🇸 Austin Krajicek defeated 🇦🇷 Máximo González / 🇧🇷 Marcelo Melo, 6–3, 6–4

Prize money

 * per team

Seeds

 * Rankings are as of May 9, 2022.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇫🇷 Hugo Gaston
 * 🇫🇷 Lucas Pouille
 * 🇫🇷 Jo-Wilfried Tsonga

The following player received entry using a protected ranking into the singles main draw:
 * Aljaž Bedene

The following players received entry from the qualifying draw:
 * 🇫🇷 Grégoire Barrère
 * 🇦🇷 Tomás Martín Etcheverry
 * 🇫🇷 Manuel Guinard
 * 🇫🇷 Gilles Simon

The following players received entry as lucky losers:
 * 🇺🇸 Michael Mmoh
 * 🇯🇵 Yosuke Watanuki

Withdrawals

 * Before the tournament
 * 🇫🇷 Benjamin Bonzi → replaced by 🇯🇵 Yosuke Watanuki
 * 🇧🇪 David Goffin → replaced by Holger Rune
 * 🇫🇷 Gaël Monfils → replaced by 🇺🇸 Michael Mmoh
 * 🇮🇹 Lorenzo Musetti → replaced by 🇰🇷 Kwon Soon-woo

Seeds

 * Rankings are as of May 9, 2022.

Other entrants
The following pairs received wildcards into the doubles main draw:
 * 🇫🇷 Ugo Blanchet / 🇫🇷 Albano Olivetti
 * 🇫🇷 Ugo Humbert / 🇫🇷 Tristan Lamasine

The following pair received entry as alternates:
 * 🇫🇷 Jonathan Eysseric / 🇫🇷 Adrian Mannarino
 * 🇺🇸 Max Schnur / 🇳🇿 Artem Sitak

Withdrawals

 * 🇩🇪 Daniel Altmaier / 🇩🇪 Oscar Otte
 * 🇦🇷 Francisco Cerúndolo / 🇦🇷 Federico Coria → replaced by 🇺🇸 Max Schnur / 🇳🇿 Artem Sitak