2022 ATP Lyon Open – Singles

Cameron Norrie defeated Alex Molčan in the final, 6–3, 6–7(3–7), 6–1 to win the singles tennis title at the 2022 ATP Lyon Open. Norrie became the first Briton to win a clay court title on the ATP Tour since 2016.

Stefanos Tsitsipas was the defending champion, but chose not to participate.

Seeds
The top four seeds receive a bye into the second round. • #🇬🇧 Cameron Norrie (champion)

• #🇪🇸 Pablo Carreño Busta (second round)

• #🇫🇷 Gaël Monfils (withdrew due to injury)

• #🇦🇺 Alex de Minaur (semifinals)

• # Karen Khachanov (second round)

• # Aslan Karatsev (first round)

• #🇦🇷 Sebastián Báez (quarterfinals)

• #🇪🇸 Pedro Martínez (first round)

Seeds
• # 🇪🇸 Carlos Taberner (first round)

• # 🇦🇷 Tomás Martín Etcheverry (qualified)

• # 🇯🇵 Yoshihito Nishioka (first round)

• # 🇸🇪 Mikael Ymer (first round)

• # 🇫🇷 Manuel Guinard (qualified)

• # 🇫🇷 Gilles Simon (qualified)

• # 🇺🇸 Michael Mmoh (qualifying competition, lucky loser)

• # 🇫🇷 Grégoire Barrère (qualified)

Qualifiers
• # 🇫🇷 Grégoire Barrère

• # 🇦🇷 Tomás Martín Etcheverry

• # 🇫🇷 Manuel Guinard

• # 🇫🇷 Gilles Simon

Lucky losers
• # 🇺🇸 Michael Mmoh

• # 🇯🇵 Yosuke Watanuki