2022 Aberto Santa Catarina de Tenis – Singles

Antonio Veić was the reigning champion but did not defend his title as he retired from professional tennis.

Igor Marcondes won the title after defeating Juan Bautista Torres 3–6, 7–5, 6–1 in the final.

Seeds
• # 🇪🇸 Fernando Verdasco (second round)

• # 🇧🇷 Orlando Luz (first round)

• # 🇦🇷 Genaro Alberto Olivieri (semifinals)

• # Gonzalo Lama (first round)

• # 🇧🇷 Igor Marcondes (champion)

• # 🇦🇷 Hernán Casanova (first round)

• # 🇪🇸 Carlos Gimeno Valero (first round)

• # 🇦🇷 Facundo Díaz Acosta (quarterfinals)