2022 Abierto Zapopan – Singles

Sloane Stephens defeated Marie Bouzková in the final, 7–5, 1–6, 6–2, to win the singles title at the 2022 Abierto Zapopan. It marked the first final and title for Stephens since 2018.

Sara Sorribes Tormo was the defending champion, but she lost in the quarterfinals to Bouzková.

Seeds
• # 🇬🇧 Emma Raducanu (first round, retired)

• # 🇺🇸 Madison Keys (first round)

• # 🇪🇸 Sara Sorribes Tormo (quarterfinals)

• # 🇨🇴 Camila Osorio (quarterfinals)

• # 🇪🇸 Nuria Párrizas Díaz (first round)

• # 🇺🇸 Sloane Stephens (champion)

• # 🇯🇵 Misaki Doi (first round)

• # 🇨🇳 Zheng Qinwen (first round)

Seeds
• # 🇭🇺 Dalma Gálfi (qualifying competition)

• # 🇮🇹 Lucia Bronzetti (qualified)

• # 🇺🇸 Hailey Baptiste (qualified)

• # 🇸🇰 Viktória Kužmová (qualified)

• # 🇪🇸 Rebeka Masarova (qualified)

• # 🇮🇹 Sara Errani (first round)

• # 🇺🇸 Christina McHale (first round)

• # 🇨🇳 Yuan Yue (first round)

• # 🇧🇾 Olga Govortsova (first round)

• # 🇯🇵 Nao Hibino (first round)

• # 🇦🇺 Storm Sanders (qualifying competition)

• # 🇺🇸 Robin Anderson (first round)

Qualifiers
• # 🇺🇸 Caroline Dolehide

• # 🇮🇹 Lucia Bronzetti

• # 🇺🇸 Hailey Baptiste

• # 🇸🇰 Viktória Kužmová

• # 🇪🇸 Rebeka Masarova

• # 🇨🇿 Brenda Fruhvirtová