2022 Adelaide International 2 – Men's singles

Thanasi Kokkinakis defeated Arthur Rinderknech in the final, 6–7(6–8), 7–6(7–5), 6–3 to win the men's singles title at the 2022 Adelaide International 2. It was his first ATP Tour title, and he won it in his hometown of Adelaide. Kokkinakis saved a match point against Marin Čilić in the semifinals.

This was the second edition of the Adelaide International for 2022.

Seeds
The top four seeds received a bye into the second round. • # 🇫🇷 Gaël Monfils (second round, retired)

• # 🇺🇸 John Isner (second round)

• # 🇷🇺 Karen Khachanov (quarterfinals)

• # Marin Čilić (semifinals)

• # Lloyd Harris (first round)

• # 🇰🇿 Alexander Bublik (first round)

• # 🇺🇸 Frances Tiafoe (first round)

• # 🇭🇺 Márton Fucsovics (second round)

Seeds
• # 🇪🇸 Roberto Carballés Baena (qualifying competition, lucky loser)

• # 🇯🇵 Yoshihito Nishioka (qualified)

• # 🇺🇸 Steve Johnson (qualified)

• # 🇩🇪 Peter Gojowczyk (withdrew)

• # 🇧🇷 Thiago Monteiro (qualifying competition, lucky loser)

• # 🇦🇷 Juan Manuel Cerúndolo (first round)

• # 🇫🇷 Corentin Moutet (qualified)

• # 🇸🇪 Mikael Ymer (withdrew)

Qualifiers
• # 🇫🇷 Corentin Moutet

• # 🇯🇵 Yoshihito Nishioka

• # 🇺🇸 Steve Johnson

• # 🇧🇾 Egor Gerasimov

Lucky losers
• # 🇧🇷 Thiago Monteiro

• # 🇪🇸 Roberto Carballés Baena