2022 Andalucía Challenger

The 2022 Andalucía Challenger (branded as the 2022 AnyTech365 Andalucía Open for sponsorship reasons) was a professional clay court tennis tournament that took place from 28 March to 3 April 2022 at the Club de Tenis Puente Romano in Marbella, Spain. It was the fifth edition of the men's event and part of the 2022 ATP Challenger Tour. It was also the first edition of the women's event and a part of the 2022 WTA 125 calendar.

Seeds

 * 1 Rankings are as of 21 March 2022.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇪🇸 Carlos Gimeno Valero
 * 🇦🇹 Dominic Thiem
 * Stan Wawrinka It was announced at the press conference that Stan Wawrinka, the former world number 3, would participate in ATP Challenger 125 in Puente Romano in Marbella. He achieved almost every possible milestone in professional tennis. Stan Wawrinka won three Grand Slam titles, 16 ATP titles and an Olympic gold in Beijing with Roger Federer in the men's doubles category.

The following players received entry into the singles main draw as alternates:
 * 🇦🇷 Pedro Cachin
 * Andrey Kuznetsov

The following players received entry from the qualifying draw:
 * 🇪🇸 Javier Barranco Cosano
 * 🇮🇹 Raúl Brancaccio
 * 🇪🇸 Carlos Gómez-Herrera
 * 🇸🇰 Lukáš Klein
 * 🇪🇸 Pol Martín Tiffon
 * Alexander Shevchenko

The following player received entry as a lucky loser:
 * 🇪🇸 Nicolás Álvarez Varona

Seeds

 * 1 Rankings are as of 21 March 2022.

Other entrants
The following players received wildcards into the singles main draw:
 * Elina Avanesyan
 * 🇪🇸 Irene Burillo Escorihuela
 * 🇪🇸 Andrea Lázaro García
 * 🇩🇪 Nastasja Schunk

The following players entered the main draw using a protected ranking:
 * 🇮🇹 Elisabetta Cocciaretto
 * 🇱🇺 Mandy Minella

Withdrawals

 * Before the tournament
 * 🇮🇹 Lucia Bronzetti → replaced by 🇩🇪 Tamara Korpatsch
 * 🇭🇺 Dalma Gálfi → replaced by 🇱🇺 Mandy Minella
 * 🇸🇰 Kristína Kučová → replaced by 🇵🇱 Katarzyna Kawa
 * 🇧🇪 Greet Minnen → replaced by 🇪🇸 Rebeka Masarova
 * 🇩🇪 Jule Niemeier → replaced by 🇨🇳 Zhu Lin
 * 🇫🇷 Diane Parry → replaced by Anna Blinkova
 * 🇦🇷 Nadia Podoroska → replaced by 🇩🇪 Anna-Lena Friedsam
 * 🇧🇪 Alison Van Uytvanck → replaced by Ekaterine Gorgodze
 * 🇧🇪 Maryna Zanevska → replaced by 🇺🇦 Lesia Tsurenko
 * 🇨🇳 Zheng Saisai → replaced by 🇷🇸 Aleksandra Krunić

Seeds

 * Rankings are as of March 21, 2022

Other entrants
The following pairs received wildcards into the doubles main draw:
 * 🇪🇸 Rebeka Masarova / 🇭🇺 Panna Udvardy

Men's singles

 * 🇪🇸 Jaume Munar def. 🇦🇷 Pedro Cachin 6–2, 6–2.

Women's singles

 * 🇪🇬 Mayar Sherif def. 🇩🇪 Tamara Korpatsch 7–6(7–1), 6–4

Men's doubles

 * 🇨🇿 Roman Jebavý / 🇦🇹 Philipp Oswald def. Hugo Nys / 🇵🇱 Jan Zieliński 7–6(8–6), 3–6, [10–3].

Women's doubles

 * 🇷🇴 Irina Bara / Ekaterine Gorgodze def. 🇩🇪 Vivian Heisen / 🇵🇱 Katarzyna Kawa 6–4, 3–6, [10–6]