2022 Andalucía Challenger – Women's singles

This was the first edition of the tournament.

Mayar Sherif won the title, defeating Tamara Korpatsch in the final, 7–6(7–1), 6–4.

Seeds
• # 🇲🇪 Danka Kovinić (semifinals)

• # Varvara Gracheva (second round)

• # 🇪🇬 Mayar Sherif (champion)

• # Arantxa Rus (second round)

• # 🇫🇷 Clara Burel (second round)

• # 🇭🇺 Panna Udvardy (quarterfinals)

• # 🇮🇹 Martina Trevisan (quarterfinals)

• # 🇸🇰 Anna Karolína Schmiedlová (quarterfinals)