2022 Argentina Open – Singles

Casper Ruud defeated the defending champion Diego Schwartzman in the final, 5–7, 6–2, 6–3 to win the singles title at the 2022 Argentina Open.

Seeds
The top four seeds received a bye into the second round. • # 🇳🇴 Casper Ruud (champion)

• # 🇦🇷 Diego Schwartzman (final)

• # 🇮🇹 Lorenzo Sonego (semifinals)

• # 🇮🇹 Fabio Fognini (quarterfinals)

• # 🇷🇸 Dušan Lajović (second round)

• # 🇦🇷 Federico Delbonis (semifinals)

• # 🇪🇸 Albert Ramos Viñolas (first round)

• # 🇷🇸 Laslo Đere (first round)

Seeds
• # 🇮🇹 Marco Cecchinato (first round)

• # 🇪🇸 Carlos Taberner (qualifying competition)

• # 🇧🇴 Hugo Dellien (qualified)

• # 🇦🇷 Francisco Cerúndolo (qualified)

• # 🇩🇪 Yannick Hanfmann (qualifying competition)

• # 🇦🇷 Tomás Martín Etcheverry (qualified)

• # 🇧🇷 Thiago Seyboth Wild (qualifying competition)

• # 🇷🇸 Nikola Milojević (first round)

Qualifiers
• # 🇦🇷 Tomás Martín Etcheverry

• # Nicolás Jarry

• # 🇧🇴 Hugo Dellien

• # 🇦🇷 Francisco Cerúndolo