2022 Aspria Tennis Cup – Singles

Gian Marco Moroni was the defending champion but withdrew from the tournament due to a back injury.

Federico Coria won the title after defeating Francesco Passaro 7–6(7–2), 6–4 in the final.

Seeds
• # 🇦🇷 Federico Coria (champion)

• # 🇫🇷 Benoît Paire (first round, retired)

• # 🇧🇴 Hugo Dellien (withdrew)

• # 🇮🇹 Gian Marco Moroni (withdrew)

• # Alexander Shevchenko (semifinals)

• # 🇮🇹 Marco Cecchinato (second round)

• # 🇮🇹 Luciano Darderi (quarterfinals, retired)

• # 🇮🇹 Francesco Passaro (final)