2022 Australian Open – Mixed doubles

Kristina Mladenovic and Ivan Dodig defeated Jaimee Fourlis and Jason Kubler in the final, 6–3, 6–4 to win the mixed doubles tennis title at the 2022 Australian Open. Though it was their first major title as a team, the win earned Mladenovic her third Mixed doubles title and Dodig his fourth.

Barbora Krejčíková and Rajeev Ram were the defending champions, but the three-time defending champion Krejčíková chose not to defend her title. Ram partnered alongside Sania Mirza, but they lost to Fourlis and Kubler in the quarterfinals.

Desirae Krawczyk was attempting to complete the first non-calendar-year Grand Slam in Mixed doubles since Billie Jean King in 1968 and would be the first in the Open Era, having won the French Open, Wimbledon and the US Open in 2021. However, she and her partner Joe Salisbury lost in the first round to Giuliana Olmos and Marcelo Arévalo.

Seeds
• # 🇺🇸 Desirae Krawczyk / 🇬🇧 Joe Salisbury (first round)

• # 🇨🇳 Zhang Shuai / 🇦🇺 John Peers (semifinals)

• # 🇺🇸 Nicole Melichar-Martinez / 🇨🇴 Robert Farah (first round)

• # Alexa Guarachi / 🇩🇪 Tim Pütz (second round)

• # 🇫🇷 Kristina Mladenovic / Ivan Dodig (champions)

• # 🇺🇸 Caty McNally / 🇬🇧 Jamie Murray (withdrew)

• # 🇷🇸 Nina Stojanović / Mate Pavić (first round)

• # 🇯🇵 Ena Shibahara / 🇯🇵 Ben McLachlan (quarterfinals)

Wild cards
• 🇦🇺 Lizette Cabrera / 🇦🇺 Alex Bolt

• 🇦🇺 Jaimee Fourlis / 🇦🇺 Jason Kubler

• 🇦🇺 Ellen Perez / Matwé Middelkoop

• 🇦🇺 Arina Rodionova / 🇦🇺 Marc Polmans

• 🇦🇺 Daria Saville / 🇦🇺 Luke Saville

• 🇦🇺 Astra Sharma / 🇦🇺 John-Patrick Smith

• 🇨🇿 Kateřina Siniaková / 🇨🇿 Tomáš Macháč

• 🇦🇺 Samantha Stosur / 🇦🇺 Matthew Ebden

Alternate pairs
• 🇷🇸 Aleksandra Krunić / 🇷🇸 Nikola Ćaćić

• 🇯🇵 Makoto Ninomiya / 🇵🇰 Aisam-ul-Haq Qureshi

Withdrawals

 * Before the tournament
 * Belinda Bencic / 🇸🇰 Filip Polášek → replaced by 🇷🇸 Aleksandra Krunić / 🇷🇸 Nikola Ćaćić
 * 🇺🇸 Caty McNally / 🇬🇧 Jamie Murray → replaced by 🇯🇵 Makoto Ninomiya / 🇵🇰 Aisam-ul-Haq Qureshi