2022 Australian Open – Wheelchair quad singles

Sam Schröder defeated the seven-time defending champion Dylan Alcott in the final, 7–5, 6–0 to win the quad singles wheelchair tennis title at the 2022 Australian Open. It marked Alcott's final professional appearance. The final was played in the Rod Laver Arena.

Seeds
• # 🇦🇺 Dylan Alcott (final)

• # Sam Schröder (champion)