2022 BBVA Open Internacional de Valencia – Singles

Martina Trevisan was the defending champion but chose not to participate.

Zheng Qinwen won the title, defeating Wang Xiyu 6–4, 4–6, 6–3 in the final.

Seeds
• # 🇪🇸 Nuria Párrizas Díaz (semifinals)

• # Varvara Gracheva (second round)

• # 🇨🇳 Zheng Qinwen (champion)

• # Arantxa Rus (quarterfinals)

• # Anastasia Potapova (second round)

• # 🇸🇰 Kristína Kučová (second round)

• # 🇷🇴 Ana Bogdan (first round)

• # 🇭🇺 Dalma Gálfi (first round)

Seeds
• # Oksana Selekhmeteva (moved to main draw)

• # 🇫🇷 Elsa Jacquemot (qualifying competition, lucky loser)

• # 🇺🇦 Katarina Zavatska (qualified)

• # 🇦🇺 Seone Mendez (qualified)

• # 🇫🇷 Carole Monnet (qualified)

• # Daniela Seguel (first round)

• # 🇪🇸 Leyre Romero Gormaz (qualified)

• # 🇪🇸 Lucía Cortez Llorca (qualifying competition)

Qualifiers
• # 🇫🇷 Carole Monnet

• # 🇪🇸 Leyre Romero Gormaz

• # 🇺🇦 Katarina Zavatska

• # 🇦🇺 Seone Mendez

Lucky loser

 * 1) 🇫🇷 Elsa Jacquemot