2022 BMW Open – Singles

Holger Rune defeated Botic van de Zandschulp in the final by retirement, 3–4 to win the singles tennis title at the 2022 Bavarian International Tennis Championships. It was Rune's first ATP Tour title, making him the third-youngest tournament champion in the Open Era and the first Dane to win an ATP title since Kenneth Carlsen at 2005 Memphis. Van de Zandschulp was also contesting for his first title in his first tour final.

Nikoloz Basilashvili was the defending champion, but lost in the quarterfinals to Miomir Kecmanović.

Seeds
The top four seeds received a bye into the second round. • # 🇩🇪 Alexander Zverev (second round)

• # 🇳🇴 Casper Ruud (quarterfinals)

• # 🇺🇸 Reilly Opelka (second round)

• # Nikoloz Basilashvili (quarterfinals)

• # Cristian Garín (first round)

• # 🇬🇧 Dan Evans (first round)

• # 🇷🇸 Miomir Kecmanović (semifinals)

• # Botic van de Zandschulp (final, retired)

Seeds
• # 🇦🇷 Francisco Cerúndolo (first round)

• # 🇯🇵 Yoshihito Nishioka (qualified)

• # Alejandro Tabilo (qualifying competition, lucky loser)

• # Henri Laaksonen (first round)

• # 🇨🇿 Jiří Lehečka (qualified)

• # 🇸🇰 Norbert Gombos (qualifying competition, lucky loser)

• # 🇧🇷 Thiago Monteiro (qualifying competition)

• # 🇩🇪 Yannick Hanfmann (qualifying competition)

Qualifiers
• # Egor Gerasimov

• # 🇯🇵 Yoshihito Nishioka

• # 🇨🇿 Jiří Lehečka

• # 🇷🇸 Marko Topo

Lucky losers
• # 🇸🇰 Norbert Gombos

• # Alejandro Tabilo